Spruance Art Center is home to the arts on campus. Its buildings house the Visual and Performing Arts Department, Spruance Art Gallery, Little Theater and Thrall Art Gallery. Located near Murphy hall, the building originally served as the powerhouse for the Harrison estate.
- Spruance Art Gallery is a nationally recognized venue for contemporary art in the greater Philadelphia area. Students have the opportunity to meet artists and work with the Gallery Director.
- Little Theater is an intimate theater. Theater Arts majors participate actively in the Theater through four MainStage productions per year as well as productions in the Black Box Theater in the Steel Building.